PROPANTHELINE

Product: 
PROPANTHELINE
Formulary: 
Generic Formulary
Category: 
Gastrointestinal Tract
Sub Group: 
SEDATIVES, ANTISPASMODICS,PARKINETICS
International Brand Name: 
Dosages: 
15 MG
Unit of Packing: 
Tablets
In treatment of: 
Management of GIT Spasm;adjunct in the treatment of Peptic Ulcer
Adverse Effects: 
1. Dry mouth 2. Nausea 3. Vomiting 4. Constipation 5. Blurred vision 6. Urinary hesitancy 7. Urine retention 8. Palpitation 9. Tachycardia 10. Headache 11. Drowsiness 12. Dizziness 13. Confusion 14. Decreased sweating 15. Urticaria
Contraiindication: 
1. Hypersensitivity to Propantheline bromide and other anticholinergic drugs 2. Narrow angle glaucoma 3. Obstructive gastro intestinal tract 4. Obstructive uropathy 5. Intestinal atony 6. Paralytic ileus 7. Severe ulcerative colitis 8. Myasthenia gravis 9. Toxic megacolon in ulcerative colitis 10.Unstable cardiovascular status in acute haemorrhage
Special Precaution: 
1.Renal impairment 2.Hepatic impairment 3.Heart failure 4.Arrhythmia 5.Hypertension 6.Coronary artery disease 7.Prostatic hypertrophy 8.Hiatus hernia associated with reflux oesophagitis 9.Hyperthyroidism 10.Pyloric stenosis
Interaction: 
Amantadine: Increase in anticholinergic side effects. Atenolol, Digoxin: Efficacy of atenolol and digoxin enhanced. Phenothiazines: Decreases antipsychotic activity, and increases anticholinergic activity. TCAs: Increased anticholinergic side effects (dry mouth, constipation, urinary retention).
Servings: 
Adult: 60 - 120 mg / day in 4 divided doses Peptic ulcer: 75 mg / day(15 mg 3 times daily

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