ANTIANGINALS & CORONORY VASOLIDATORS
International Brand Name:
1.Congestive heart failure is precipitated or aggravated; 2.Decreases coronary blood flow; 3.Forgetfulness; 4.Nightmares; 5.Decreases exercise capacity; 6.Decreases carbohydrate tolerance ; 7.Decrease insulin release; 8.Increases free fatty acid levels and increase LDL to HDL ratio; 9.Worsens chronic obstructive lung diseases; 10.Gastrointestinal problems
1.Hypersensitivity to the drug; 2.Second or third degree heart block; 3.Congestive heart failure; 4.Cardiogenic shock; 5.Bradycardia; 6.Chronic obstructive pulmonary diseases; 7.Hypoglycemia; 8.Haemorrhage
1.Peripheral arterial diseases; 2.Ischaemic heart disease; 3.Congestive heart failure ; 4.Renal impairment ; 5.Hepatic impairment; 6. Diabetes mellitus; 7. The drug should be gradually withdraw with caution; 8. Non allergic bronchospastic diseases; 9. Thyrotoxicosis; 10. Along with other antihypertensive drugs
Quinidine: Orthostatic hypotension.; Rifampicin, Phenobarbital, NSAIDs, Thyroid hormones, Smoking: Decrease antihypertensive action of propranolol.; Corticosteroids: Antagonism of hypotensive effect.; Sympathomimetics: Marked hypertension and bradycardia.; Insulin: Hypoglycemic effects prolonged by propranalol and masking of symptoms of hypoglycemia in diabetes.; Lidocaine: Increased levels of lidocaine may occur resulting in toxicity.; Calcium channel blockers: Severe bradycardia especially in hose with impaired LV function.
40 to 240mg/day; Hypertension: Starts with 80mg once daily or in 2 divided doses and gradually ncreases up to 320mg/day based on patient`s response in divided doses 12th hourly or 8th hourly.; Maximum daily dose: 640mg.; Sustained release formulations: 120 to 160mg/day. Once daily.; Children: 1mg/kg/day gradually increases to 4mg/kg/day based on patient`s response in 4 divided doses; Maximum dose: 5mg/kg/day.; Arrhythmias & Anxiety: 30mg to 150mg/day in 3 to 5 divided doses.; Children: 0.5 to 4mg/kg/day in 3 to 4 divided doses.