RANITIDINE

Product: 
RANITIDINE
Formulary: 
Generic Formulary
Category: 
Gastrointestinal Tract
Sub Group: 
Hyper Acidity,Reflux,Ulcers
International Brand Name: 
Zantac
Dosages: 
150 MG/300 mg
Unit of Packing: 
Tablets
In treatment of: 
Benign Gastric & Duodenal Ulceration
Adverse Effects: 
1. Headache 2. Dizziness 3. Constipation 4. Vertigo 5. Confusion 6. Rash 7. Blurred vision 8. Thrombocytopenia 9. Leukopenia
Contraiindication: 
1. Hypersensitivity to Ranitidine
Special Precaution: 
1. Hepatic impairment 2. Renal impairment 3. Acute Porphyria
Interaction: 
Antacids: Ranitidine absorption may be decreased. Diazepam: Efficacy of diazepam decreased. Procainamide: Renal clearance of procainamide decreased. Sulfonylureas: Hypoglycemic effects of glipizide enhanced. Theophyllines: Increased efficacy of theophyllines with possible toxicity. Warfarin: Increased hypoprothrombinemic effects. Lab tests: False positive tests for urine proteins with multistix may occur.
Servings: 
Adult: 300mg / day Duodenal ulcer, benign gastric ulcer: 300 mg /day as single dose at bed time or in 2 divided dose (morning and bed time) for minimum of 4 weeks. Maintenance dose: 150 mg / day at bed time. Zollinger- Ellison syndrome: 300 - 450 mg / day in 2 - 3 divided doses; dose can be increased if necessary to a maximum up to 6g / day . Gastroesophageal reflux: 300 mg / day as single dose at bed time or in 2 divided doses (morning and bed time) for maximum 2 months. In severe conditions dose can be increased to 600 mg / day in 4 divided doses for 3 months Acid indigestion, Heart burn, Sour stomach: Dose: 75 mg once daily to a maximum up to 150 mg / day. Oesophagitis: 150 mg/ day. Dyspepsia: 75 - 300 mg / day depending on the severity of disease. PAM: 150mg given night and in the morning before surgical procedures. Children: Duodenal ulcer, benign gastric ulcer: 4 - 8 mg / kg body weight / day in 2 divided doses. Maximum dose: 300 mg / day

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