International Brand Name:
In treatment of:
Management of Hyper Tension(HTN)
4.Increased gut motility
6.A-V conduction blocks
2.In patients receiving electro convulsive therapy
Antihypertensives / Diuretics: Antihypertensive effects are enhanced.
Digitialis and Quinidine: May result in cardiac arrhythmias.
Ephedrine or Mephentermine: Hypertension may occur.
General anaesthesia: Hypotension and bradycardia may occur.
Levodopa: Signs and symptoms of Parkinsonism may be exacerbated.
MAOIs: Should be avoided since it may result in hypertension.
Sympathomimetics: Reserpine prolongs sympathomimetic response of direct acting and inhibits of indirect acting sympathomimetics.
TCAs: Results in a response refractory to TCA therapy. Also hypotension, flushing, diarrhoea and manic reactions may occur.
Lab tests: Increased serum prolactin levels, decreased urinary excretion of catecholamines, 17-ketosteroids, 17-hydroxycorticosteroids (17-OCHS) and vanillyl mandelic acid (VMA).
250 to 500mcg/day, gradually reduce to maintenance dose of 250mcg/day
Maximum dose: 1mg to 1.5 mg