RIZATRIPTAN

Product: 
RIZATRIPTAN
Formulary: 
Generic Formulary
Category: 
Pain & Fever
Sub Group: 
ANTIMIGRAINE DRUGS
International Brand Name: 
Rizaliv, Rizalt
Dosages: 
5 MG/10 mg
Unit of Packing: 
Tablets
In treatment of: 
Acute treatment of Migrane attacks
Adverse Effects: 
1. Dizziness 2. Drowsiness 3. Palpitation 4. Dry mouth 5. Diarrhoea 6. Nausea 7. Vomiting 8. Dyspnea 9. Flushing 10.Increased blood pressure
Contraiindication: 
1. Hypersensitivity to Rizatriptan 2. Ischaemic heart diseases 3. Angina pectoris 4. Myocardial infarction 5. Coronary artery vasospasm 6. Uncontrolled hypertension 7. Patient on monoamine oxidase inhibitor therapy
Special Precaution: 
1. Hepatic impairment 2. Renal impairment 3. Hypertension 4. Hypercholesterolemia 5. Diabetes 6. Obesity 7. Family history of coronary artery disease 8. Women with surgical menopause 9. Smoking
Interaction: 
Antibacterials: quinolones possibly reduce metabolism of Rizaitriptan. Avoid concomitant use with clarithromycin and erythromycin. Antidepressants: risk of CNS toxicity with MAOIs. Beta blockers: Propranolol may increase plasma concentration of Rizatriptan. Ergotamine: Increased risk of vasospasm.
Servings: 
Adult: 5 - 10mg at the beginning of headache and if sufficient response does not obtain then repeat the dose after 2 hours, maximum dose: 30mg / day. Patient taking Propranolol the maximum dose is 15mg/ day Children: Not recommended

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