ROSUVASTATIN

Product: 
ROSUVASTATIN
Formulary: 
Generic Formulary
Category: 
Cardio Vascular System
Sub Group: 
LIPID LOWERING AGENTS
International Brand Name: 
Crestor
Dosages: 
5 MG/ 10 mg
Unit of Packing: 
Tablets
In treatment of: 
Primary hyper cholesterolaemia (Type II A including heterozygous failial hyper cholesterolaemia (tyoe II B),including familial hyper cholesterolaemia as an adjunct to diet and Exercise
Adverse Effects: 
1.Headache 2.Dizziness 3.Insomnia 4.Asthenia 5.Abdominal discomfort 6.Heart burn 7.Abdominal pain 8.Nausea 9.Dyspepsia 10.Flatulence 11.Constipation 12.Abnormal liver function tests 13.Rash 14.Fatigue 15.Myositis 16.Chest pain 17.Myopathy 18.Upper respiratory tract infections
Contraiindication: 
1.Hypersensitivity to the drug 2.Active liver diseases 3.Persistent elevation of serum transaminase levels 4.Severe renal impairment
Special Precaution: 
1.Monitor hepatic and renal function tests and lipid levels before and periodically during therapy and stop drug if there is marked elevation of creatinine phosphokinase level 2.History of liver diseases 3.Alcoholics 4.In severe adverse effects and Myopathy
Interaction: 
Rosuvastatin appears to have a low propensity for pharmacokinetic drug interactions. Caution should be exercised in patients receiving concomitant cyclosporin.
Servings: 
Oral: Initially 5mg to 10mg once daily; increased if required at four week intervals based on patient`s response. Maximum dose: 40mg

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