SISOMICIN

Product: 
SISOMICIN
Formulary: 
Generic Formulary
Category: 
Infections & Infestations
Sub Group: 
ANTIBACTERIALS
International Brand Name: 
Dosages: 
100MG/ 50 mg
Unit of Packing: 
Inj- 1ml
In treatment of: 
Treatment of susceptible GM-Ve and Staphylococcal infections
Adverse Effects: 
1. Transient irritation in the eye 2.Ototoxicity
Contraiindication: 
1. Hypersensitivity to Sisomicin and other Fluoroquinolones
Special Precaution: 
1. Prolonged use 2. Stop the use of medicaments if allergic reactions occur 3. Avoid contact lenses 4. Wear sun glasses if sensitivity to sunlight occurs
Interaction: 
Aminoglycosides, Amphotericin B, Bacitracin, Cisplatin, Cephalothin, Vancomycin, Methoxyflurane Ethacrynic Acid, Frusemide, Bumetanide & Mannitol: Increased ototoxic, neurotoxic or nephrotoxic affects. Anaesthetics, Neuromuscular blocking agents (Tubocurarine, Gallamine): Risk of neuromuscular blockade and respiratory paralysis. Penicillin, Cephalosporins, Carbenicillin, Ticarcillin: Exert antibiotic synergism, especially useful in pseudomonas infections. Lab tests: Aminoglycoside serum levels: Guard against in-vitro inactivation of aminoglycosides by b-lactum antibiotics in patients on combination therapy.
Servings: 
The usual dose for adults is 3 mg/kg daily given intramuscularly in 2 or 3 divided doses. It may be given by intravenous infusion if necessary. Adult: 1 - 2 drop to be instilled in to the infected eye every 4-6 hours Trachoma: Treatment is for 1 - 2 months

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