TERBUTALINE

Product: 
TERBUTALINE
Formulary: 
Generic Formulary
Category: 
Respiratory System
Sub Group: 
ANTIASTHAMATICS
International Brand Name: 
Brethine, Bricanyl, Brethaire
Dosages: 
2.5 MG ; 5 MG; 1.5 MG/5ML; 0.5 MG/ML; 250 MCG/1PUFF; 10 MG/ML; 5 MG; 7.5 MG
Unit of Packing: 
Tablets/ Capsules/ Bottles/ Inhalers
In treatment of: 
Acute Bronchospasm
Adverse Effects: 
1. Drowsiness 2. Headache 3. Dizziness 4. Nervousness 5. Tremor 6. Weakness 7. Palpitations 8. Tachycardia 9. Arrhythmia 10. Vomiting 11. Nausea 12. Heartburn 13. Diaphoresis 14. Dry and irritated nose (inhalation) 15. Hypokalaemia (high dose)
Contraiindication: 
1. Hypersensitivity to Terbutaline and other sympathomimetic amines.
Special Precaution: 
1. Myocardial insufficiency 2. Arrhythmia 3. Hypertension 4. Hyperthyroidism 5. Epilepsy 6. Diabetes
Interaction: 
Other Sympathomimetic bronchodilators or epinephrine: Combined effect on the cardiovascular system may be deleterious to the patient. MAOIs and TCAs: Effect of terbutaline on vascular system may be potentiated. Beta-adrenergic blocking agents: Block the pulmonary effect of terbutaline and may produce severe asthmatic attacks in asthmatic patients. Beclomethasone, Theophylline: Synergy when used with these agents. Food: Reduces bioavailability of terbutaline.
Servings: 
Adult: Oral: Initial dose: 7.5 mg / day in 3 divided doses, if needed dose can be increased to 15mg /day in 3 divided doses. Subcutaneous /Intramuscular/slow IV infusion: 250 - 500mcg 3 - 4 times daily Aerosol inhalation: 250 - 500mcg every 6 - 8 hours Nebulised solution inhalation: 5 - 10 mg every 6 - 12 hours. Children: Oral: Initial dose: 2.5 mg in 2-3 times daily Subcutaneous /Intramuscular/slow IV infusion: 10mcg /kg body weight dose can be increased to 300 mcg / day Aerosol inhalation: 250 - 500mcg every 6 - 8 hours Nebulised solution inhalation: 2 - 5 mg every 6 - 12 hours. Premature labor (IV): Initial dose: 10mcg/minute and dose can be repeated until effective therapeutic response is obtained. Maximum dose: 80mcg/minute. Maintenance dose (IV dosage): Minimum effective dose for 4 hours.

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