TIBOLONE

Product: 
TIBOLONE
Formulary: 
Generic Formulary
Category: 
Endocrine System
Sub Group: 
GONADOL HORMONE & RELATED DRUGS
International Brand Name: 
Dosages: 
2.5 MG
Unit of Packing: 
Tablets
In treatment of: 
Treatment of menopausal vasomotor symptoms and prevention of post menopausal Osteoporosis
Adverse Effects: 
1.Weight gain 2.Vaginal spotting(occasional) 3.Increased facial hair 4.Ankle oedema 5.Headache 6.Dizziness 7.Depression 8.Gastrointestinal disturbances 9.Abdominal pain 10.Arthralgia 11.Myalgia 12.Rashes 13.Pruritus 14.Migraine 15.Visual disturbances 16.Changes in liver function tests
Contraiindication: 
1.Hormone dependent carcinoma 2.Undiagnosed vaginal bleeding 3.Thromboembolic disorders 4.Severe liver diseases 5.Cardiovascular diseases 6.Cerebrovascular diseases
Special Precaution: 
1.Use only after 12 months of last menstrual period 2. Migraine 3.Epilepsy 4.Renal impairment 5.Hepatic impairment 6.Cholestatic jaundice 7.Hypercholesterolemia 8.Diabetes mellitus
Interaction: 
Antibacterials: Rifampicin: Accelerates metabolism (reduced plasma concentration). Antiepileptics: Carbamazapine, phenobarbitone, phenytoin, primidone: Accelerate metabolism.
Servings: 
Oral: 2.5mg/day

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