TICLOPDINE

Product: 
TICLOPDINE
Formulary: 
Generic Formulary
Category: 
Cardio Vascular System
Sub Group: 
ANTI COAGULANTS THROMBOLYTICS & ANTIPLATLET DRUGS
International Brand Name: 
Ticlid
Dosages: 
250 MG
Unit of Packing: 
Vial
In treatment of: 
Prevention of Thrombotic strokes
Adverse Effects: 
1. Diarrhoea, 2. Vomiting, 3. Nausea, 4. Abdominal pain, 5. Headache, 6. Tinnitus, 7. Rash, 8. Haemorrhage, 9. Neutropenia, 10. Thrombocytopenia, 11. Vasculitis, 12. Nephrotic syndrome, 13. Jaundice.
Contraiindication: 
1. Hypersensitivity to the drug, 2. Haemorrhagic disorders, 3. Gastrointestinal tract ulcer, 4. Intracranial haemorrhage, 5. Severe renal impairment, 6. Severe hepatic impairment.
Special Precaution: 
1. Haemopoetic disorders, 2. Renal impairment, 3. Hepatic impairment, 4. Trauma, 5. Recent surgery.
Interaction: 
Antacids: Absorption of ticlopidine decreased. Cimetidine: Chronic cimetidine administration results in decreased clearance of ticlopidine. Aspirin: Effect of aspirin on collagen induced platelet aggregation potentiated hence coadministation not recommended. Digoxin: Digoxin levels may be slightly decreased. Theophylline: Elimination half life of theophylline increased significantly.
Servings: 
Oral: 250mg 12th hourly with meals.

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